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. 2022 May 31;12(4):469–480. doi: 10.1016/j.jobcr.2022.05.014

Table 3.

Details of intervention (photobiomodulation).

S.No Author Laser type Wavelength Model (Manufacturer) Output power (mW) Fluence/Energy density (J/cm2) Total dose per tooth Site of application Duration and frequency
1 Goymen et al. 201927 GaAlAs laser device
LED application according to the manufacturer's instructions with an 850-nm wavelength
Laser - 810-nm
LED – 850 nm
Cheese dental laser; Wuhan Gigaa Optronics Technology Co. Ltd., Wuhan, China
OrthoPulse, Biolux Research Ltd., Vancouver, BC, Canada
Not reported Laser - 8 J/cm2
LED - 20 mW/cm2
10 points total Laser - 0, 3, 7, 14, 21 and 28 days
LED -10 min per day
2 Fernandes et al. 201926 Diode laser 808 nm Laser Duo, MMOptics, São Carlos, SP, Brazil 100 mW Beam area = 0.04 cm2
Energy density - 25 J/cm2
10 points on the gingival tissue (five points per vestibular and five per palatine region): two points on the cervical third (one mesial and one distal gingiva), two points on the apical third (one mesial and one distal), and one point in the middle third (root center) 10 s per point
Three different moments: immediately after force application (T0), after 3 (T1) and 7 days (T2), as well as, whenever a new elastic chain was placed to activate the intrusion, during a total of 3 months
3 Khaw et al. 201825 Aluminum-gallium-indium-phosphorus laser 660 nm Thor Photomedicine, Buckinghamshire, United Kingdom 75-mW Power density of 0.245 W/cm2
Fluence of 3.6 J/cm2
1/e2 spot size - 0.260 cm2,
1/e2 power density - 0.245 W/cm2
Total energy - 7.6 J 4 points buccally and 4 palatally
2 points at the cervical portion (mesial and distal), 1 at midroot, and 1 at the apex of the tooth per buccal and lingual sides
15 s per point
LLLT regimen was performed at weekly sessions over a period of 6 weeks
4 Okla et al. 201824 850 nm OrthoPulse®
Biolux Research Ltd., Vancouver, BC, Canada
Not reported Continuous wave, 0.065 J/cm2 Complete arch 5 min per arch per day
5 Ng et al. 201723 AlGaAs
Aluminum-gallium-Arsenic
808 nm Klas, Konftec Corporation, Taiwan Continuous mode- 180 mW

Pulsed mode- 360 mW at 20 Hz
Beam area of 0.5 cm2
Total irradiated surface area was 4 cm2
1.6 J per point 4 buccal, 4 palatal points
Apex, Middle third (centre of the root), Cervical third (mesial) and Cervical third (distal)
Continuous laser - 9 s per point
Pulsed laser - 4.5 s per point
Days 0,1,2,3, 7, 14, 21.
6 Sousa et al. 201121 Aluminum-gallium-arsenide (AsGaAl) 780 nm Twin Laser (MM Optics Ltda, São Carlos, São Paulo, Brazil) 20 mW 5 J/cm2
Irradiated area of about - 0.04 cm2
0.2 J of energy per point
Total – 2J
10 s per point
Day 0, 3, 7, 30 and 60