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. Author manuscript; available in PMC: 2022 Jun 9.
Published in final edited form as: J Neurochem. 2015 Sep 2;135(3):466–478. doi: 10.1111/jnc.13233

Fig. 2.

Fig. 2

Resveratrol prevents Cd from reducing cell viability and altering cell morphology in neuronal cells. PC12 cells and/or primary neurons were pre-treated with resveratrol (Res, 0–100 μM for 1 h, and then exposed to Cd (10 and 20 μM for 24 h. (a) Live cells were detected by counting viable cells using trypan blue exclusion, showing that Res rescued PC12 cells from Cd-induced reduction of cell viability concentration-dependently. (b) Morphology of PC12 cells and primary neurons was visualized under a Nikon Eclipse TE2000-U inverted phase-contrast microscope (200×) equipped with a digital camera. Scale bar: 100 μm. Results are presented as mean ± SE, n = 5. Using one-way anova, ap < 0.05, difference with control group; bp < 0.05, difference with 10 μM Cd group; cp < 0.05, difference with 20 μM Cd group.