Table 4.
Diagnostic capacity of the microscopic examination in comparison with the PCR assay.
| Pathogens | Sensitivity % (95% CI) | Specificity % (95% CI) | PPV (95% CI) | NPV (95% CI) | Cohen’s kappa coefficient (k) (95% CI) | Z value | Degree of agreement |
|---|---|---|---|---|---|---|---|
| E. canis | 0 (0-63.2) | 100 (97.8-100) | 47.8 (10.4-83.0) | 97.5 (96.6-98.4) | 0 (0-0) | NA | No agreement |
| A. platys | 15.4 (5.4-31.8) | 100 (97.4-100) | 84.2 (42.7-94.3) | 84.6 (82.7-86.6) | 0.23 (0.04-0.42) | 2.38 | Fair |
| H. canis | 75 (24.9-98.7) | 100 (97.8-100) | 77.7 (31.7-90.0) | 99.1 (97.5-99.5) | 0.85 (0.57-1.00) | 5.91 | Very good |
PPV=Positive predictive value, NPV=Negative predictive value, NA=Not available, PCR=Polymerase chain reaction, CI=Confidence interval