Skip to main content
. Author manuscript; available in PMC: 2022 Sep 29.
Published in final edited form as: AAPS PharmSciTech. 2021 Sep 29;22(7):240. doi: 10.1208/s12249-021-02108-5

Table 3:

Drug-release kinetics of PQ-SLN-2, PQ-NLC-2, and PQ-NE-2 formulations.

Formulation Zero order model Higuchi model Korsmeyer-Peppas model Hixon–Crowell model

R2 k R2 k R2 n k R2 k

PQ-SLN-2 at pH 1.2 0.4 31.69 0.5 38.67 0.88 0.57 1.03 0.39 0.99
PQ-NLC-2 at pH 1.2 0.47 29.11 0.59 37.37 0.9 0.57 0.95 0.4 0.94
PQ-NE-2 at pH 1.2 0.44 29.20 0.55 36.72 0.91 0.59 0.96 0.35 0.94
PQ-SLN-2 at pH 6.8 0.73 16.09 0.9 30.13 0.92 0.67 0.6 0.65 0.34
PQ-NLC-2 at pH 6.8 0.64 19.62 0.82 31.84 0.92 0.65 0.7 0.5 0.39
PQ-NE-2 at pH 6.8 0.6 22.53 0.77 33.91 0.94 0.65 0.79 0.45 0.49