Table 1.
Baseline Characteristics, Overall and Stratified by Vaccination Period
| Overall | Unvaccinated Period | Partially Vaccinated Period | Vaccinated Period | Vaccine-Boosted Period | P Value* | |
|---|---|---|---|---|---|---|
| Patients in vaccine period, n | 7094 | 7094 | 3898 | 3253 | 1053 | |
| Total patient-days in vaccine period | 19,77,412 | 10,62,752 | 1,85,506 | 6,51,706 | 77,448 | |
| Days in vaccination period: mean (SD) | 276.46 (104.89) | 149.81 (115.44) | 47.59 (62.61) | 200.34 (77.01) | 73.55 (69.64) | |
| Mortality: n (%) | 904 (12.7) | 598 (8.4) | 75 (1.9) | 197 (6.1) | 36 (3.4) | <0.001 |
| Age: mean (SD) | 73.27 (14.48) | 73.27 (14.48) | 73.90 (13.84) | 74.19 (13.58) | 75.91 (12.23) | <0.001 |
| Sex: male (%) | 3719 (52.4) | 3719 (52.4) | 2021 (51.8) | 1671 (51.4) | 559 (53.1) | 0.68 |
| Race/ethnicity: n (%) | <0.001 | |||||
| White | 2360 (33.3) | 2360 (33.3) | 1308 (33.6) | 1106 (34.0) | 432 (41.0) | |
| Asian | 353 (5.0) | 353 (5.0) | 208 (5.3) | 179 (5.5) | 53 (5.0) | |
| Black/African American | 1826 (25.7) | 1826 (25.7) | 998 (25.6) | 821 (25.2) | 237 (22.5) | |
| Hispanic | 1571 (22.1) | 1571 (22.1) | 962 (24.7) | 816 (25.1) | 237 (22.5) | |
| Other/Multiracial | 741 (10.4) | 741 (10.4) | 345 (8.9) | 272 (8.4) | 79 (7.5) | |
| Unknown | 243 (3.4) | 243 (3.4) | 77 (2.0) | 59 (1.8) | 15 (1.4) | |
| Insurance: n (%) | <0.001 | |||||
| Private | 994 (14.0) | 994 (14.0) | 584 (15.0) | 512 (15.7) | 159 (15.1) | |
| Medicaid | 704 (9.9) | 704 (9.9) | 328 (8.4) | 241 (7.4) | 49 (4.7) | |
| Medicare | 4493 (63.3) | 4493 (63.3) | 2568 (65.9) | 2165 (66.6) | 758 (72.0) | |
| Other | 903 (12.7) | 903 (12.7) | 418 (10.7) | 335 (10.3) | 87 (8.3) | |
| Smoking status (n, (%)) | <0.001 | |||||
| Nonsmoker | 4198 (59.2) | 4198 (59.2) | 2145 (55.0) | 1791 (55.1) | 557 (52.9) | |
| Former smoker | 2380 (33.5) | 2380 (33.5) | 1513 (38.8) | 1272 (39.1) | 447 (42.5) | |
| Current smoker | 516 (7.3) | 516 (7.3) | 240 (6.2) | 190 (5.8) | 49 (4.7) | |
| Medical history: n (%) | ||||||
| Pulmonary disease: n (%) | 1255 (17.7) | 1255 (17.7) | 787 (20.2) | 657 (20.2) | 244 (23.2) | <0.001 |
| Immunological disease: n (%) | 169 (2.4) | 169 (2.4) | 123 (3.2) | 102 (3.1) | 38 (3.6) | 0.018 |
| Cerebrovascular disease: n (%) | 958 (13.5) | 958 (13.5) | 568 (14.6) | 476 (14.6) | 165 (15.7) | 0.132 |
| Cardiovascular disease: n (%) | 5529 (77.9) | 5529 (77.9) | 3227 (82.8) | 2707 (83.2) | 923 (87.7) | <0.001 |
| Liver disease: n (%) | 206 (2.9) | 206 (2.9) | 125 (3.2) | 103 (3.2) | 47 (4.5) | 0.06 |
| Obesity: n (%) | 738 (10.4) | 738 (10.4) | 477 (12.2) | 387 (11.9) | 132 (12.5) | 0.008 |
| Hypertension: n (%) | 4139 (58.3) | 4139 (58.3) | 2529 (64.9) | 2122 (65.2) | 739 (70.2) | <0.001 |
| Chronic kidney disease: n (%) | 1789 (25.2) | 1789 (25.2) | 1108 (28.4) | 947 (29.1) | 344 (32.7) | <0.001 |
| Diabetes n (%) | 2272 (32.0) | 2272 (32.0) | 1376 (35.3) | 1149 (35.3) | 399 (37.9) | <0.001 |
⁎
P values from comparisons between patients between time periods, not including overall column.