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. 2022 Jun 9;28(9):1475–1479. doi: 10.1016/j.cardfail.2022.05.008

Table 2.

Summary of Regression Models for Hospitalization, ICU Admission and Mortality

Statistic Reference Level Coefficient Estimate (95% CI) P Value
Model 1: Mortality* Hazard ratio (HR) Unvaccinated Partially vaccinated 0.87 (0.68, 1.12) 0.28
Fully vaccinated 0.36 (0.30, 0.43) <0.001
Boosted 0.33 (0.23, 0.48) <0.001
Model 2: Hospitalization Count Incidence rate ratio (IRR) Unvaccinated or partially vaccinated Fully vaccinated or vaccine-boosted 0.68 (0.65, 0.71) <0.001
Model 3: ICU Admission Count Incidence rate ratio (IRR) Unvaccinated or partially vaccinated Fully vaccinated or vaccine-boosted 0.63 (0.58, 0.68) <0.001

Inverse probability treatment-weighted model with time-dependent covariate for vaccination.

Negative binomial regression model for count of hospitalizations.

Negative binomial regression model for count of ICU admissions.

Adjustment covariates: age, sex, race/ethnicity, insurance, smoking, pulmonary disease, immunological disease, liver disease, obesity, hypertension, chronic kidney disease, diabetes.