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. 2022 Jun 9;20:133. doi: 10.1186/s12915-022-01338-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Syntenic relationships in anole lizard, wallaby, and human. Gene positions (blue boxes) in vicinity of autosomal PRSSLYL in anole lizard and X-linked PRSSLX in wallaby, as well as syntenic region on human X chromosome, which is missing a PRSSLY homolog, are shown. Gene positions based on genome assemblies for anole lizard chr1 (Broad AnoCar2.0/anoCar2) and human X chromosome (GRCh38/hg38). The genome assembly for wallaby does not provide sufficient X coverage, but an X-chromosome-derived BAC sequence is available (accession number CU234131) that contains PRSSLX and upstream genes. Dashed lines connect homologous genes