Clinical and circuit characteristics associated with bleeding events. Factors associated with any bleeding events and medical bleeding (including intracranial hemorrhage, pulmonary and gastrointestinal bleeding). AdjOR, adjusted odds ratio; CI, confidence interval; ECMO, extracorporeal membrane oxygenation; PaCO2, arterial partial pressure of carbon dioxide; P/F, PaO2/FiO2 ratio. The unit of observation for all models is the patient. *p < 0.05; **p < 0.01; ***p < 0.001