Table 3. Enriched TB-related pathways of macrophage subclusters by KEGG analysis.
Subclusters | 2 | 3 | 6 |
TB: tuberculosis; KEGG: Kyoto Encyclopedia of Genes and Genomes. | |||
Enriched genes of TB-related pathways | HLA-DMA, HLA-DMB, LAMP1, STAT1, ITGB2, CALM3, CD14, CTSD, ATP6V0D2, CTSS, HLA-DQA1 | CIITA, CEBPB, TGFB1, ITGAM, STAT1, IFNGR2, ITGB2, CORO1A, HSPD1, FCGR3A, FCGR2A, MRC1, CD14, CALM1, FCGR2B, JAK1 | FCER1G, STAT1, RIPK2, IFNGR2, IL18, TNF, CTSS, NFKB1, IL1A, IL1B, CD14, FCGR1A, CLEC4E, BID, HLA-DQA1, TLR2 |
Count | 11 | 16 | 16 |
Gene ratio | 0.063 | 0.052 | 0.072 |
False discovery rate | 0.016 | <0.001 | <0.001 |
Adjusted P-value | 0.017 | <0.001 | <0.001 |