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. 2022 Jun 9;10(11):1049–1060. doi: 10.1016/S2213-2600(22)00163-1

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© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license

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Kinetics of immune response over time with all schedules normalised by time of second dose in the seronegative general cohort

Figure shows results for anti-spike IgG titres (A) and T-cell ELISpot counts (B). Day 0 refers to time of second dose. Datapoints are geometric mean concentrations, with whiskers showing the 95% CIs. Numbers of participants per timepoint are shown in the appendix (p 16). ELU=exponential linear unit. PBMCs=peripheral blood mononuclear cells. SFC=spot-forming cell.