Skip to main content
. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: J Immunol. 2022 May 13;208(11):2461–2465. doi: 10.4049/jimmunol.2200175

Figure 3. Spike peptide pools induce a greater helper (CD4+) T cell response than cytotoxic (CD8+) T cell response.

Figure 3.

A) representative flow cytometric plot of spike peptide induction of expression of costimulatory molecules CD137 and OX-40 on CD3+CD4+ T cells. B) Number of CD4+ cells expressing CD137 and OX-40 was higher than for CD8 T cells. Kruskal-Wallis test with Dunn’s correction for multiple comparisons C) IL-17a and D) IL-4 were reduced in response to Omicron peptides in subjects which received two doses of mRNA vaccines. Two-tailed Wilcoxon rank test. N=96. Data presented as mean ± standard error of the mean. Data from one experiment.