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. 2022 Jun 9;4(7):e542–e557. doi: 10.1016/S2589-7500(22)00091-7

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© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Kaplan-Meier curve of cumulative COVID-19 events in vaccinated and unvaccinated individuals

Cumulative proportion of individuals with a positive SARS-CoV-2 test (A), primary care diagnosis (B), hospital admission (C), ventilatory support (D), and COVID-19 mortality (E) in matched groups of fully vaccinated (two doses administered at least 14 days before Feb 1, 2021) and unvaccinated individuals (no doses administered before or during follow-up). Analysis was run from Feb 1, 2021 to March 15, 2021 and individuals were matched on the basis of sex, 5-year age groups, and ethnicity. Shaded areas show 95% CIs. Log-rank p<0·0001, for all subplots.