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Effects of COX-2 deficiency on the HCD and KRASG12D/+ mediated pancreatic inflammation and immune cell infiltration. (A). Immunohistochemical analyses of mouse pancreata from the indicated four groups with antibodies against COX-2, F4/80, CD3, CD4, and CD8. Magnification: 200×. (B–F). Quantification of IHC stains of COX-2, F4/80, and CD3, CD4, and CD8, respectively. NS, not significant. ****, p-value < 0.0001.
