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. 2022 May 24;11(11):1730. doi: 10.3390/cells11111730

Figure 3.

Figure 3

Macrophage subtypes in DRG of old WT and GLA KO mice. (A–F) Representative photomicrographs of F4/80+ (A,D), CD80+ (B,E), and CD206+ (C,F) macrophages (arrowheads) in DRG of old WT and old GLA KO mice. (G) Quantification of F4/80+ pan-macrophages per mm² DRG area in old WT (◯, n = 5) and old GLA KO mice (●, n = 5). (H) Quantification of CD80+ M1 macrophages per mm² DRG area in old WT (◯, n = 5) and old GLA KO mice (●, n = 5). (I) Quantification of CD206+ M2 macrophages per mm² DRG area in old WT (◯, n = 5) and old GLA KO mice (●, n = 5). Abbreviations: CD = Cluster of Differentiation; DAPI = 4′,6-diamidino-2-phenylindole; DRG = dorsal root ganglia; GLA KO = alpha-galactosidase A knockout; WT = wildtype. Scale bar: 25 µm. ** p < 0.01.