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The targetable mutations that are approved by the Food and Drug Administration or used in the clinical trial European Society for Medical Oncology Scale of Clinical Accountability for molecular targets (ESCAT) and OncoKB
|
Mutation
|
ESCAT/OncoKB, Tier
|
| TP53 | X |
| BRAF | III |
| CCNE | X |
| EGFR | III |
| PIK3CA | III |
| FGFR1 | III |
| RB1 | X |
| KIT | III |
| PDGFRA | III |
| RAF1 | III |
| ERBB2 | III |
| MET | III |
