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. 2022 May 27;14(11):2671. doi: 10.3390/cancers14112671

Figure 3.

Figure 3

Chemotherapy regimen and number of cycles, by age at diagnosis. (A) Chemotherapy regimen for the total population (n = 91,938). Raw data for subgroups representing less than 2% of the total population are not displayed on the graph to ensure readability. In the anthracyclines group, n = 773 (0.8%); (B) Chemotherapy regimen, by age class at BC diagnosis. Raw data for subgroups representing less than 2% of the corresponding age class are not displayed on the graph, to ensure readability. The values are: for the <30 years old class: n = 12 (1.4%), 30–39 years old: n = 122 (1.5%), 40–49 years old: n = 361 (1.5%), 50–59 years old: n = 485 (1.9%) for the paclitaxel group. In the <30 years old class: n < 10, 30–39 years old: n = 49 (0.6%), 40–49 years old: n = 203 (0.9%), 50–59 years old: n = 205 (0.8%), 60–69 years old: n = 202 (0.9%), 70–79 years old: n = 90 (0.9%), and ≥80 years old: 17 (1.2%) for the anthracyclines group; (C) Chemotherapy regimen, by age at BC diagnosis. The cohort is restricted to patients aged from 25 to 86 years (n = 91,750); (D) Number of chemotherapy cycles for the total population. The number of chemotherapy cycles was calculated by setting (n = 85,752). A patient with six cycles of neoadjuvant chemotherapy followed by four cycles of adjuvant chemotherapy was counted as having both six cycles and four cycles of treatment. Settings with missing numbers of chemotherapy cycles are not displayed (n = 6186). Raw data for subgroups representing less than 2% of the total population are not displayed on the graph, to ensure readability: 1443 (1.7%) settings are in the more than 9 cycles group; (E) Number of chemotherapy cycles by age class (n = 85,752) at BC diagnosis. Raw data for subgroups representing less than 2% of the corresponding age class are not displayed on the graph, to ensure readability. The values are: for the 40–49 years old class: n = 441 (2.0%), 50–59 years old: n = 412 (1.7%), 60–69 years old: n = 271 (1.3%), 70–79 years old: n = 98 (1.1%), and ≥80 years old: n = 22 (1.7%) for the more than 9 cycles group; and (F) Chemotherapy regimens by age at BC diagnosis. The cohort is restricted to patients aged from 25 to 86 years (n = 85,589). Abbreviations: BC = breast cancer, More than 9 = more than 9 cycles, 8 = 8 cycles, 7 = 7 cycles, 6 = 6 cycles, 5 = 5 cycles, 4 = 4 cycles, Less than 3 = less than 3 cycles.