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. 2022 May 28;11(11):1770. doi: 10.3390/cells11111770

Figure 1.

Figure 1

Increased lipid ROS and differentiation deficits in 5×FAD NSC’s: (A). Graphical representation of culturing NSC’s from 5×FAD and WT. (B). Western blots and densitometric analysis showing increased APP levels in 5×FAD NSC’s. (C). Florescence microscopy images representing increased lipid ROS levels in 5×FAD cells compared to WT via fluorescence intensity of Liperfluo dye. (D). Flow cytometry quantification of lipid ROS showing higher fluorescence of Liperfluo in 5×FAD cells compared to WT cells. (E). Western blot representing expression of Tuj1, GFAP and SNAP-25 in 5×FAD and WT NSC’s. (F). Densitometric analysis indicating levels of Tuj1, GFAP and SNAP in differentiated WT and 5×FAD cultures. *: p < 0.05; **: p < 0.01.