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. 2022 May 26;14(11):2637. doi: 10.3390/cancers14112637
CAFs cancer-associated fibroblasts
CAV1 caveolin1
CD29 integrin β1
COL11A1 collagen type XI alpha 1 chain
CXCR4 C-X-C chemokine receptor type 4
CXCL12 C-X-C chemokine ligand 12
CXCL14 C-X-C chemokine ligand 14
ECM extracellular matrix remodeling
EMT epithelial-mesenchymal transition
ERK extracellular signal-regulated kinase
FAK focal adhesion kinase
FAP fibroblast activation protein
FGF-1 fibroblast growth factor-1
GRP78 glucose-regulating protein 78
HGF hepatocyte growth factor
GPR77 G protein-coupled receptor 77
MAPK mitogen-activated protein kinase
MCT4 monocarboxylate transporters 4
MDSCs myeloid-derived suppressor cells
MMP3 matrix metalloproteinase-3
MSCs mesenchymal stem cells
PARP poly ADP-ribose polymerase
PDAC pancreatic ductal adenocarcinoma
PDGF platelet-derived growth factor
PI3K phosphatidylinositol 3-kinase
PDGFRα/β platelet-derived growth factor receptor-α/-β
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PS-1 presenilin-1
p38αMAPK p38alpha mitogen-activated protein kinase
STAT3 signal transducer and activator of transcription 3
TGF-β transforming growth factor-beta
TIME tumor immune microenvironment
TME tumor microenvironment
VCAN versican
α-SMA α-smooth muscle actin