CAFs |
cancer-associated fibroblasts |
CAV1 |
caveolin1 |
CD29 |
integrin β1 |
COL11A1 |
collagen type XI alpha 1 chain |
CXCR4 |
C-X-C chemokine receptor type 4 |
CXCL12 |
C-X-C chemokine ligand 12 |
CXCL14 |
C-X-C chemokine ligand 14 |
ECM |
extracellular matrix remodeling |
EMT |
epithelial-mesenchymal transition |
ERK |
extracellular signal-regulated kinase |
FAK |
focal adhesion kinase |
FAP |
fibroblast activation protein |
FGF-1 |
fibroblast growth factor-1 |
GRP78 |
glucose-regulating protein 78 |
HGF |
hepatocyte growth factor |
GPR77 |
G protein-coupled receptor 77 |
MAPK |
mitogen-activated protein kinase |
MCT4 |
monocarboxylate transporters 4 |
MDSCs |
myeloid-derived suppressor cells |
MMP3 |
matrix metalloproteinase-3 |
MSCs |
mesenchymal stem cells |
PARP |
poly ADP-ribose polymerase |
PDAC |
pancreatic ductal adenocarcinoma |
PDGF |
platelet-derived growth factor |
PI3K |
phosphatidylinositol 3-kinase |
PDGFRα/β |
platelet-derived growth factor receptor-α/-β |
PFKFB2 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
PS-1 |
presenilin-1 |
p38αMAPK |
p38alpha mitogen-activated protein kinase |
STAT3 |
signal transducer and activator of transcription 3 |
TGF-β |
transforming growth factor-beta |
TIME |
tumor immune microenvironment |
TME |
tumor microenvironment |
VCAN |
versican |
α-SMA |
α-smooth muscle actin |