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Mean change in left ventricular ejection fraction by visit. CL, confidence limit; ddAC, dose-dense doxorubicin plus cyclophosphamide; DPH, docetaxel, pertuzumab, and trastuzumab; FEC, fluorouracil, epirubicin, and cyclophosphamide; TPH, paclitaxel, pertuzumab, and trastuzumab.
