Table 1. Relationship between patient characteristics and fibrinogen/albumin ratio.
| Characteristic | Low FARa | Middle FARa | High FARa | P value |
|---|---|---|---|---|
| Age (years, mean ± SD) | 47.38 ± 13.70 | 53.76 ± 12.57* | 58.86 ± 13.17*# | <0.001 |
| Gender (male), n (%) | 48 (65.8) | 38 (53.5) | 41 (55.4) | 0.274 |
| BMI (kg/m2, mean ± SD) | 22.56 ± 3.56 | 23.16 ± 3.27 | 23.85 ± 3.86 | 0.097 |
| Smokers, n (%) | 22 (30.1) | 21 (29.6) | 16 (21.6) | 0.430 |
| Drinkers (alcohol), n (%) | 13 (17.8) | 8 (11.3) | 13 (17.6) | 0.472 |
| Primary disease, n (%) | 0.269 | |||
| Chronic glomerulonephritis | 29 (39.7) | 24 (33.8) | 39 (52.7) | |
| Chronic nephrotic syndrome | 26 (35.6) | 23 (32.4) | 10 (13.5) | |
| Hypertensive nephropathy | 4 (5.5) | 4 (5.6) | 8 (10.8) | |
| Diabetic nephropathy | 2 (2.7) | 11 (15.5) | 10 (13.5) | |
| Otherb | 12 (16.4) | 9 (12.7) | 7 (9.5) | |
| CKD stage, n (%) | 0.343 | |||
| 3 | 14 (19.2) | 4 (5.6) | 4 (5.4) | |
| 4 | 2 (2.7) | 3 (4.2) | 2 (2.7) | |
| 5 | 11 (15.1) | 14 (19.7) | 18 (24.3) | |
| 5d | 16 (63.0) | 50 (70.4) | 50 (67.6) | |
| Dialysis modality, n (%) | 0.073 | |||
| No dialysis | 27 (37.0) | 21 (29.6) | 24 (32.4) | |
| Hemodialysis | 42 (57.5) | 37 (52.1) | 29 (39.2) | |
| Peritoneal dialysis | 4 (5.5) | 13 (18.3) | 11 (28.4) | |
| Hypertension, n (%) | 51 (69.9) | 54 (76.1) | 54 (73.0) | 0.705 |
| Diabetes mellitus, n (%) | 5 (6.8) | 15 (21.1)* | 19 (25.7)* | 0.008 |
| Anti-hypertensive agent, n (%) | ||||
| Calcium channel blocker | 42 (57.5) | 46 (64.8) | 44 (59.5) | 0.654 |
| β-blocker | 24 (32.9) | 20 (28.2) | 22 (29.7) | 0.821 |
| Angiotensin-aldosterone antagonists | 21 (28.8) | 17 (23.9) | 19 (25.7) | 0.800 |
| Insulin, n (%) | 2 (2.7) | 13 (18.3)* | 12 (16.2)* | 0.003 |
| Recombinant human erythropoietin injection, n (%) | 41 (56.2) | 45 (63.4) | 43 (58.1) | 0.661 |
| Levocarnitine injection, n (%) | 37 (50.7) | 31(43.7) | 24 (32.4) | 0.150 |
| Calcium-containing phosphate binders, n (%) | 23 (31.5) | 30 (42.3) | 26 (35.1) | 0.395 |
| Non-calcium-based phosphate binders, n (%) | 13 (17.8) | 13 (18.3) | 10 (13.5) | 0.691 |
| Nutritional/active vitamin D, n (%) | 21 (30.0) | 28 (40.0) | 21 (30.0) | 0.273 |
| Calcimimetics, n (%) | 3 (4.1) | 5 (7.0) | 5 (6.8) | 0.698 |
Notes.
- BMI
- body mass index
- CKD
- chronic kidney disease
- SD
- standard deviation
a
Low FAR group (n = 73): FAR ≤ 0.079; medium FAR group (n = 71): 0.079 < FAR ≤ 0.102; high FAR group (n = 74): FAR > 0.102.
b
Other primary disease includes lupus nephritis, polycystic kidney disease and IgA nephropathy.
*
compared with low FAR group, P < 0.05.
#
compared with middle FAR group, P < 0.05.