Table 1.

Univariate and multivariate Cox analyses of Sig27var25 component genes in predicting ACC poor OS and progression.

	Univariate Cox Analysis			Multivariate Cox Analysis 1
Gene 2	HR	95% CI	p-Value	HR	95% CI	p-Value
Poor OS
LINC01089	1.002	1–1.003	0.0479 *	1.002	0.9997–1.003	0.101
RGS11	1	1–1.001	0.0291 *	1	1–1.001	0.0697
MXD3	1.003	1.002–1.004	8.53 × 10−7 ***	1.003	1.0016–1.004	2.75 × 10−5 ***
BIRC5	1.003	1.002–1.004	1.45 × 10−9 ***	1.002	1.0014–1.003	8.79 × 10−7 ***
RAB30	1.008	1.003–1.013	0.00283 **	1.006	1.001–1.012	0.0122*
worse PFS
LCN12	1.007	1.001–1.013	0.0187 *	1.011	1.0004–1.018	0.00172 **
VGF	1	1–1	0.00124 **	1	1–1	0.0463 *
RGS11	1.001	1–1.001	0.00271 **	1.001	1.0001–1.001	0.0207 *
MXD3	1.002	1.001–1.003	0.000676 ***	1.0017	1.0005–1.003	0.00495 **
BIRC5	1.002	1.001–1.002	6.13 × 10−5 ***	1.001	1.0002–1.002	0.0196 *
RAB30	1.02	1.005–1.014	1.92 × 10−5 ***	1.0099	1.0053–1.014	1.94 × 10−5 ***
NOD2	1.007	1.001–1.014	0.0237 *	1.0064	1.0003–1.012	0.0394 *
ZFHX4	1	1–1.001	0.035 *	1.001	1.0001–1.001	0.0235 *

¹: In analysis with age at diagnosis and tumor stage (stage 1 (3 + 4) vs. stage 0 (1 + 2)); ²: continuous gene expression data were used in analysis; * p < 0.05; ** p < 0.01; *** p < 0.001.