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SFN increased global histone acetylation in PSCs. (A): The HDAC activity in Ctrl and SFN treated PSCs; (B): HDAC family members’ relative mRNA expression levels; (C,D): Western blot results of acetylated histone H3 and H4 in PSCs treated with Ctrl and SFN, and Coomassie-Brilliant Blue staining as loading control. Data are shown as the mean ± SE and assays were done in triplicates. * p < 0.05, ** p < 0.01, *** p < 0.001.
