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. 2022 May 26;12(11):1365. doi: 10.3390/ani12111365

Figure 7.

Figure 7

SFN upregulated SMAD7 expression in PSCs. SFN enriched the histone H4 acetylation level in the SMAD7 promoter and suppressed the expression of miRNAs targeting SMAD7, which led to increased mRNA and protein abundance of SMAD7 in PSCs.