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. 2022 Apr 14;94(22):7731–7737. doi: 10.1021/acs.analchem.1c04407

Figure 1.

Figure 1

Phylogeny depicting unexplained sequence alterations introduced to the clone 1 anti-lysosome RNA aptamer7 collected 01/01/2020. (A) The nodes in the artificial phylogenetic trees represent groupings of aptamers according to unexplained sequence alterations. (B) Reprinted with permission ref (7). Copyright 2001 Elsevier. (C) Reprinted in part with permission from ref (12). Copyright 2004 American Chemical Society. (D) Unexplained sequence alterations were classified into categories.