Table 1. Unexplained Sequence Alterations Introduced to the Clone 1 Anti-Lysosome RNA Aptamer7a.
node | # | aptamer sequence reported |
---|---|---|
1 | 4 | GGGAAUGGAUCCACAUCUACGAAUUCAUCAGGGCUAAAGAGUGCAGAGUUACUUAGUUCACUGCAGACUUGACGAAGCUU |
2A | 4 | biotin-24polyT-GGGAATGGATCCACATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGTTCACTGCAGACTTGACGAAGCTT |
2B | 20 | GGGAATGGATCCACATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGTTCACTGCAGACTTGACGAAGCTT |
2C | 1 | GGGAAUGGAUCCACAUCUACGAAUUCAUCAGGGCUAAAGAGTGCAGAGUUACUUAGUUCACUGCAGACUUGACGAAGCUU |
2D | 1 | GGGAAUGGAUCCACAUCUACGAAUUCAUCAGGGCUAAAGAGUGCAGAGUUACUUAGUUCACUGCAGACUUGACGAAGCUU |
3A | 25 | GGGAATGGATCCACATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGTTCACTGCAGACTTGACGAAGCTT |
3B | 1 | HS-(CH2)6-GGGAATGGATCCACATCTACGAATTCATCAGGGCTAAAGAGTGCAGAGTTACTTAGGGGCGCTTCACTGCAGACTTGACGAAGCTT |
3C | 1 | GGGAATGGATCCACCAGTGTATCTACGAATTCATCAGGGCTAAAGAGTGAAGAGTTACTTAGTTCACTGCAGACTTGACGAAGCTT |
4A | 1 | GGGAATGGATCCACATCTACGAATTCdithiolTTTTTTATCAGGGCTAAAGAGTGCAGAGTTACTTAGTTCACTGCAGACTTGACGAAGCTT |
0 | 2 | no sequence in text or supplement |
Unexplained insertions are bold. Unexplained substitutions are bold and underlined. Unexplained deletions are struck out, and justified or explained alterations are in light grey. The number (#) column indicates the number of publications found reporting each sequence in our analysis.