Table 2.
Top up regulated proteins differentially expressed associated with cognitive decline. A comparison of TAC-treated mice versus saline-treated mice identified 192 proteins as meeting statistical significance for differential expression.
| Protein | Description | Location | Type | Fold Change (log ratio) |
|---|---|---|---|---|
| Q5JC28 | Epidermal growth factor receptor pathway substrate 15 isoform B (Epidermal growth factor receptor substrate 15) | Other | 2.26 | |
| Q8CBF3 | Ephrin type-B receptor 1 (EC 2.7.10.1) | Plasma membrane, Endosomes, Dendrites | 3.73 | |
| D6RDE8 | Desumoylating isopeptidase 1 | Other | 2.19 | |
| Q7TQF2 | F-box only protein 10 | Other | 2.69 | |
| Q61112 | 45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4) | Golgi apparatus | 3.71 | |
| A0A140LIJ4 | Dynein, axonemal, heavy chain 14 | Cytoskeleton | 5.00 |