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. 2022 Jun 2;14(11):2772. doi: 10.3390/cancers14112772

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Hormesis effect of BDE209 on Nthy-ori 3-1 and PTC cell invasion and migration. (A) Wound-healing assay was performed to assess the mobility of TPC-1 and BCPAP cells treated with different concentrations of BDE209 compared with the negative controls. Representative images are shown on the left, and the statistical analysis is shown on the right. (B) The effects of RUVBL1 on cell migration. TPC-1 and BCPAP cell lines were treated as indicated and evaluated by Transwell migration assays. Top panel: Representative images of cell migration. Bottom panel: Quantitative results of the migration assays. * p < 0.05, ** p < 0.01, and *** p < 0.001, based on Student’s t-test. Each experiment was repeated at least three times.