Figure 6.

Alterations in TCR Vβ clonotypes in the peripheral blood of patients with localized prostate cancer. A number of TCR Vβ clonotypes with ascending (left chart) and descending (right chart) CFs, as well as the emergence of new clonotypes (left chart) with increased frequency pre- and post-RT were identified. Clonotypes with increased CFs post-RT entered the top 10 TCR Vβ CFs. Note that C2, C7, C10, C13, C19, and C20, which are presented amongst clonotypes with increased CFs, were actually new clonotypes that emerged post-RT (indicated with an asterisk). Clonotypes with decreased CFs post-RT were excluded from the top 10 TCR Vβ CFs (although they were part of the top 10 TCR CFs before RT). RT, radiotherapy; CF, clonal frequency; TCR Vβ, T-cell receptor variable β.