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. Author manuscript; available in PMC: 2022 Jun 9.
Published in final edited form as: J Med Chem. 2021 Jun 4;64(12):8755–8774. doi: 10.1021/acs.jmedchem.1c00758

Figure 1.

Figure 1.

Structurally diverse enterovirus 2C inhibitors. The hit compound 7a identified from our high-throughput screening served as a starting point for the lead optimization in this study.