TABLE 2.
Clinical, lipids and inflammation parameters of the study population according to OSA severity.
| Variable | AHI | ||
|---|---|---|---|
| I ≤ 15 per h (n = 97) | II ≥ 15, but <30 per h (n = 83) | III ≥30 per h (n = 148) | |
| Glucose (mmol/L) | 5.7 (5.4–6.0) | 6.1 (5.705–6.530) | 6.3 (5.991–6.684) a |
| Creatinine (umol/L) | 81.3 (77.6–85.0) | 84.2 (80.4–88.0) | 90.8 (87.2–94.4) a , b |
| Uric acid (umol/L) | 337.6 (316.2–359.0) | 327.6 (307.8–347.4) c | 375.7 (359.4–391.9) a , b |
| Albumin (g/L) | 45.1 (44.1–46.1) | 43.3 (42.1–44.5) | 44.8 (44.1–45.5) |
| Direct bilirubin (U/L) | 2.4 (2.2–2.7) | 2.6 (2.2–3.0) | 2.4 (2.2–2.7) |
| Total bilirubin (U/L) | 12.6 (11.4–13.8) | 13.3 (11.3–15.2) | 12.5 (11.2–13.7) |
| AST (U/L) | 21.6 (20.1–23.2) | 21.7 (19.2–24.1) | 25.3 (21.9–28.7) a |
| ALT (U/L) | 24.8 (21.3–28.2) | 22.8 (18.1–27.4) | 31.6 (26.1–37.2) a , b |
| CK (U/L) | 96.7 (84.4–109.0) | 102.8 (85.0–120.6) | 135.8 (94.6–177.0) a |
| Gama GT (U/L) | 32.2 (24.3–40.1) | 27.5 (22.0–33.0) | 36.7 (30.9–42.6) |
| Microalbumine/Creatinine Ratio | 1.8 (0.15–3.5) | 1.9 (1.1–2.7) | 10.1 (2.6–17.6) a , b |
| Triglyceride (mmol/L) | 1.8 (1.6–2.0) | 1.9 (1.7–2.1) c | 2.3 (2.1–2.5) a , b |
| Total cholesterol (mmol/L) | 4.7 (4.3–5.0) | 3.4 (3.0–3.9) | 3.7 (3.3–4.0) a |
| HDL (mmol/L) | 1.3 (1.2–1.4) | 1.3 (1.2–1.4) | 1.2 (1.1–1.2) a |
| LDL (mmol/L) | 3.6 (3.4–3.8) | 3.6 (3.4–3.8) | 3.6 (3.4–3.8) |
| Non-HDL (mmol/L) | 4.3 (4.1–4.5) | 4.3 (3.9–4.7) | 4.3 (4.0–4.6) |
| Total chol./HDL-C | 4.4 (4.2–4.8) | 4.7 (4.3–5.1) | 4.9 (4.6–5.2) a |
| LDL-C/HDL-C | 2.8 (2.6–3.0) | 2.9 (2.5–3.2) | 2.9 (2.7–3.2) |
| CRP * (mg/L) | 2.3 (0.9–5.7) | 4.0 (1.4–6.0) | 4.5 (2.0–8.0) a , b |
| ESR * (mm/h) | 14.0 (7.0–20.0) | 13.5 (10.0–25.0) | 17.0 (10.5–26.5) a |
Data are presented as mean (95%CI).
*
Median (25–75th Percentile).
a
III, vs. I < 0.05.
b
III, vs. II < 0.05.
c
II, vs. I < 0.05.