Table 4.
Major disulfide bonds identified for the precursor Δ1-2SRCR-LOXL2 and the 2HP inhibited mixture of Δ1-3SRCR-LOXL2.
| Peptide (#) | Domain | Disulfide | Δ1-2SRCR-LOXL2 | Δ1-3SRCR-LOXL2 |
|---|---|---|---|---|
| Precursor | Mixture | |||
| 6 | SRCR3 | Cys351–Cys414 | ✓ | − |
| 7 | Cys364–Cys424 | ✓ | − | |
| 8 | Cys395–Cys405 | ✓ | − | |
| 9 | SRCR4 | Cys464–Cys530 + Cys477–Cys543 |
✓ | ✓ |
| 10 | Cys511–Cys521 | ✓ | ✓ | |
| 11 | Amine oxidase domain | Cys573–Cys625 + Cys579–Cys695 |
✓ | ✓ |
| 12 | Cys657–Cys673 + Cys663–Cys685 |
12a | 12a + 12b | |
| 13 | Cys732–Cys746 | ✓ | ✓ |
The peptide number (#) is from Table 3.