Table 1.

Involvement of miR-202 in Breast Cancer progression and suppression.

mir-202 Function	Regulation (Up/Down)	Patients’ Samples, Cell Lines, Animal Model	Involved Downstream/Upstream Molecules	Ref.
pro-tumorigenic	up	23 DOX-resistant, 39 DOX-sensitive BC cancer samples, cells lines, xenografted nude mice	PTEN/PI3k/Akt	[13]
pro-tumorigenic	up	BC cell lines	PTEN/PI3k/Akt	[17]
pro-tumorigenic	up	45 pairs of BC cancer and adjacent normal tissue, cell lines	lncRNA GSEC, AXL	[14]
pro-tumorigenic	up (early stage)	Plasma samples of 30 BC patients (stages I–III), 30 control samples	n.d.	[11]
pro-tumorigenic	up	Sera of 102 BC patients and 26 with benign breast diseases, blood samples of 37 healthy controls	n.d.	[10]
pro-tumorigenic	up (early stages)	Blood samples of 48 early-stage BC and 57 controls	n.d.	[9]
suppressor	down	27 BC tissue samples, cell lines	ROCK1, E-cadherin, Twist, N-cadherin, and MMP2	[18]
suppressor	down	BC cell lines	MMP-1, claudin-5, ZO-1 and ß-catenin	[16]
suppressor	down	30 BC tissues	KRAS	[15]

n.d. = no data.