Table 3.

miR-202 is a potential tumor suppressor in lung cancer.

mir-202 Function	Regulation	Samples, Cell Lines, Patient Material, Animal Model	Involved Downstream/Upstream Molecules	References
suppressor	down	56 patient tissues and corresponding normal tissues, cell lines	STAT3	[46]
suppressor	down	40 lung adenocarcinoma and adjacent normal tissue samples	KCNK15-AS1, EGFR, miR-202/miR-370/EGFR axis	[48]
suppressor	down	40 NSCLC tissues, cell lines	MALAT1	[49]
suppressor	down	25 NSCLC and adjacent paratumor tissues, cell lines, mouse xenografts	KRAS	[47]
suppressor	down	cell lines	NORAD	[50]
suppressor	down	20 lung cancer and adjacent normal tissues	cyclin D1	[45]
suppressor	down	26 tumor and corresponding normal lung tissue samples	n.d.	[44]
suppressor	down	Nude mice, cell lines		[34]
pro-tumorigenic	up	125 plasma samples first-line chemotherapy	Macrophage Polarization	[8]

n.d. = no data.