Table 1.
Characteristics | RE Group (n = 10) |
NR Group (n = 5) |
p Value |
---|---|---|---|
Sex, n (%) | 0.167 | ||
Men | 8 (80) | 2 (40.0) | |
Women | 2 (20) | 3 (60.0) | |
Age, median (IQR), years | 40 (26.8–54) | 53 (30–64.5) | 0.312 |
Duration of disease, median (IQR), years | 3.5 (0.9–10.8) | 2 (1.3–3.7) | 0.258 |
Disease extent, n (%) | 0.167 | ||
E1 Proctitis | 5 (50) | 1 (20) | |
E2 Left-sided colitis | 2 (20) | 4 (80) | |
E3 Pancolitis | 3 (30) | 0 (0) | |
Concomitant medication, n (%) | 1.000 | ||
None | 0 | 0 | |
Oral steroids | 1 (10) | 0 | |
5-ASA | 10 (100) | 5 (100) | |
Immunomodulator | 1 (10) | 0 | |
Biologics | 0 | 0 | |
Total Mayo scores | 0.899 | ||
mean (SD) | 5.5 (1.6) | 5.4 (0.9) | |
range | 4–9 | 5–7 | |
Endoscopic Mayo scores | 0.558 | ||
mean (SD) | 2 (0.7) | 2.2 (0.4) | |
range | 1–3 | 2–3 | |
Nancy index, mean (SD) | 2.8 (0.4) | 2.8 (0.4) | 1.000 |
Inflammatory index, median (IQR) | |||
WBC count, ×109/L | 8 (5.7–10.2) | 6.8 (5.1–9.1) | 0.426 |
Neutrophils count, ×109/L | 5.1 (3.4–8.0) | 4.4 (2.8–7.5) | 0.681 |
CRP, mg/L | 1.6 (0.4–6.3) | 1.3 (0.2–4.5) | 0.477 |
ESR, MM/H | 12.5 (5.8–27) | 5 (3.5–27.5) | 0.599 |
PLT count, ×109/L | 268.5 (212.5–323.3) | 220 (199–243) | 0.145 |
Nutritional index, median (IQR) | |||
BMI, kg/m2 | 21.2 (19.7–27.2) | 22.5 (18.8–24.7) | 0.612 |
Hemoglobin, g/L | 147 (131.8–154.3) | 123 (115.5–154.5) | 0.406 |
Albumin, g/L | 44.1 (40.6–45.4) | 41.9 (40.7–44.3) | 0.706 |
RE, responders; NR, non-responders; WBC, white blood cell; CRP, C reactive protein; ESR, erythrocyte sedimentation rate; PLT, platelet; BMI, body mass index.