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Clinical features of patients PT4 and PT33. (A,B) Facial features of PT4 at 3 and 9 years of age. (C,D) Frontal and profile facial features of PT33 at age 23 years. (E) Secondary dentition of PT33 showing wide upper central incisors (11 mm). (F) Foot of PT33 with large hallux. (G,H) Small hands of PT33 with hypoplasia of the 1st and 5th metacarpal bones and of the intermediate phalanx of the 2nd finger, bilaterally.
