Table 1.
The parameters of morphometry of the aorta of rat treated with different immunosuppressive drugs protocols.
| Control (n = 6) |
TRG (n = 6) |
CRG (n = 4) |
MRG (n = 6) |
CMG (n = 6) |
TMG (n = 6) |
|
|---|---|---|---|---|---|---|
| Width of Tunica Media (µm) | ||||||
| AM ± SD | 65.4 ± 3.09 | 79.83 ± 2.95 | 49.81 ± 3.34 | 75.71 ± 5.34 | 88.06 ± 2.87 | 123.81 ± 6.05 |
| Median | 65.3 | 79.75 * | 50.3 *,T | 76.0 * | 88.15 *,T | 122.3 * |
| Min–max | 61.6–70 | 74.3–84.0 | 44.7–53.6 | 69.7–88.1 | 83.5–93.0 | 117.1–133.6 |
| Distance between elastic lamellae in Tunica Media (µm) | ||||||
| AM ± SD | 9.26 ± 2.38 | 10.48 ± 2.82 | 9.62 ± 3.11 | 18.54 ± 24.41 | 10.2 ± 1.98 | 19.52 ± 5.41 |
| Median | 9.75 | 10.65 | 8.65 | 14.6 * | 9.7 | 17.45 *,T |
| Min–max | 3.3–14.6 | 4.8–14.8 | 2.6–19.1 | 5.9–143.0 | 6.6–13.7 | 11.5–39.0 |
| Number of vascular smooth muscle cells nuclei in Tunica Media | ||||||
| AM ± SD | 53.83 ± 4.53 | 72.33 ± 3.14 | 54 ± 7.48 | 39.66 ± 6.12 | 99.50 ± 10.05 | 138.66 ± 8.14 |
| Median | 55.5 | 72.5 * | 55.0 T | 39.0 *,T,C | 98.50 *,T,C,M | 139.0 *,T,C,M |
| Min–max | 46.0–58.0 | 68.0–77.0 | 44.0–62.0 | 32.0–50.0 | 89.0–111.0 | 128.0–151.0 |
AM: arithmetic mean; SD: standard deviation; n—number of measured parameters, Min–Max—minimum and maximum values; * p < 0.05 vs. control; T p < 0.05 vs. TRG; C p < 0.05 vs. CRG; M p < 0.05 vs. MRG.