ABL	ABL tyrosine-protein kinase
AIF	apoptosis-inducing factor
AKT	serine/threonine-protein kinase
AO/EB	Acridine orange/ethidium bromide
BBB	blood–brain barrier
BTK	Bruton’s tyrosine kinase
CA	carbonic anhydrase
CDK	cyclin-dependent kinases
Csp3	carbons in the sp3 hybridization
CYP	cytochrome P450
DMSO	dimethyl sulfoxide
FBS	fetal bovine serum
HIA	human gastrointestinal absorption
ICAM-1	intercellular adhesion molecule 1
MEM	amino acids solution
MMP	mitochondria membrane potential
mTOR	mechanistic target of the rapamycin
MTT	3-(4,5-dimethylthiazol-2-yl)-2,3-diphenyltetrazolium bromide
MW	molecular weight
PBS	buffered saline
PD-1	programmed death receptor-1
PDB	protein data bank
PD-L1	programmed death ligand-1
PGP	glycoprotein P
PI3K	phosphoinositide-3-kinase
PTEN	phosphatase and tensin homolog
RMSD	root mean square deviation
RMSF	root mean square fluctuation
TP53	cellular tumor antigen p53
TPSA	topological polar surface area