Skip to main content
. 2022 May 24;23(11):5864. doi: 10.3390/ijms23115864

Figure 4.

Figure 4

CCI induces a significant increase in the proportion of astrocytes and microglia in dorsal horns reversed by the MOR and DOR agonist LP2. (a–f) Representative pictures of Gfap- (a) and Iba1- (d) positive cell and quantification on laminae I-IV of the (b,e) and (c,f) dorsal horn of the lumbar region of the spinal cord. CCI, chronic constriction injury; NLX, naloxonazine; NTD, naltrindole; FC, fold change. * p-value < 0.05, ** p-value < 0.01, and *** p-value < 0.001 versus sham or between groups.