Figure 1.

Study design. In vitro fracture model adopted by Sundelacruz et al. [23]: unseeded GHA or GHAZOL scaffolds are inserted between the two halves of scaffold cultured for three days with hMSCs differentiated into osteoblastic lineage to evaluate cell morphology, viability, osteogenic differentiation extracellular matrix deposition and the presence of inflammatory cytokines at the selected experimental times of 3, 7 and 10 days.