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Calcitonin gene-related peptide receptor, a complex heterotrimeric G-protein-coupled receptor, consists of the calcitonin-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and a small receptor component protein (RCP). CLR includes 7 transmembrane proteins (TM1–7), whereas RAMP1 is a single transmembrane protein. PM—plasma membrane.
