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. 2022 May 25;11(11):2995. doi: 10.3390/jcm11112995

Table 1.

Baseline correlation analysis and best model of determinants of GFR and intrarenal resistive index.

GFR Intrarenal RI
Variable Correlation Coefficient Best Model
Standard Coefficient
Correlation Coefficient Best Model
Standard Coefficient
Age (years) −0.313 *** −0.192 * 0.175 * -
Male sex (yes/no) 0.109 - 0.099 -
Past or active smoker (yes/no) 0.068 - 0.044 -
History of (yes/no):
  • Hypertension

  • Diabetes

  • Coronary artery disease

  • Heart failure

  • Atrial fibrillation

  • Tia/stroke

  • Peripheral artery disease


−0.019
0.128
0.049
−0.120
−0.030
−0.064
−0.084

-
-
-
-
-
-
-

0.110
0.071
0.046
0.143
0.064
−0.018
0.133

-
-
-
-
-
-
-
Body mass index (kg/m2) −0.054 - 0.011 -
Systolic blood pressure (mm Hg) 0.110 0.132 −0.081 -
Pulse pressure (mm Hg) 0.080 - 0.041 -
Plasma glucose levels (mg/dL) −0.085 - 0.091 -
Total cholesterol (mg/dL) −0.157 −0.187 * −0.244 ** -
Non-HDL cholesterol (mg/dL) −0.121 - −0.270 ** −0.308 ***
Triglycerides (mg/dL) 0.041 - −0.010 -
Statin user (yes/no) 0.045 - 0.254 ** -
Serum creatinine (mg/dL) −0.545 *** - 0.347 *** -
Serum uric acid (mg/dL) −0.120 - 0.098 -
GFR (mL/min/1.73 m2) - - −0.299 *** −0.383 ***
24-h urinary albumin (mg/day) −0.002 - 0.005 -
24-h urinary protein (mg/day) −0.014 - 0.014 -
Longitudinal kidney diameter (mm) 0.331 *** 0.175 * 0.051 -
Kidney cortical thickness (mm) 0.362 *** 0.233 ** 0.008 0.127
Intrarenal RI −0.299 *** −0.311 *** - -

* p < 0.050; ** p < 0.010; *** p < 0.001; RI, resistive index; Tia, transitory ischemic attack; GFR, glomerular filtration rate by creatinine clearance.