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. 2022 Jun 5;23(11):6320. doi: 10.3390/ijms23116320

Figure 1.

Figure 1

Representative CTCs recovered from the four BC patients enrolled. (A–F) Classical CTCs, identified as round, middle-sized cells; CD45-negative, EpCAM-/CD44-positive or -negative, and Hoechst-positive cells. (A,D) EpCAM-positive CTCs; (B,F) CD44-positive CTCs; (C) heterogeneous CTC cluster (composed of one EpCAM-positive cell and one CD44-positive cell); (E) EpCAM- and CD44-negative CTC. (G,H) “Non-conventional” CTCs, identified as small-sized CD45-negative and CD44-positive cells; (I) example of leukocyte (CD45-positive and, very often, CD44-positive cells).