Table 2.
The potential of neuroimaging methods in detecting AD.
| Method | Sensitivity | Specificity | Accuracy | Pros | Cons | Refs. |
|---|---|---|---|---|---|---|
| MRI | 80–95% | 55–98% | 89–97% | Spatial resolution | Temporal resolution, MR exposure | [36,105,106,107,108] |
| FDG-PET | 43–100% | 57–100% | 50–100% | Clear image | FDG injection | [44,47,57,63,109] |
| fNIRS | 82–94% | 72–88% | 50–90% | High speed, portability | Spatial resolution | [110,111] |
| fMRI | 84–94% | 68–91% | 75–93% | Spatial resolution | Not portable/Expose MR | [78,80,112] |
| EEG | 35–88% | 82–100% | 62–92% | High speed, portability | Spatial resolution | [99,101,103,113,114] |
MRI, magnetic resonance imaging; FDG-PET, fluorodeoxyglucose-positron emission tomography; fNIRS, functional near-infrared spectroscopy; fMRI, functional MRI; EEG, electroencephalography.