Figure 13.
(A) Chemical structure of fusicoccin A (FC-A), FC-NAc, FC-NCPC, and FC-NCHC as MG compounds; (B) a cartoon model to show the key finding for potential disease treatment. This type of MG compound could strengthen some 14-3-3 clients’ binding to 14-3-3, while disrupting other clients’ binding on 14-3-3 as shown in (B).