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Molecular mechanisms of PLOD2 in GBM. (A) Representative western blots of Catenin D1, CD44, CD99, MT1-MMP and PLOD2 levels in sh-PLOD2 versus sh-control GBM cells. Beta-actin was used as a loading control. PLOD2 knock-down significantly decreased the levels of (B) Catenin D1, (C) CD44, (D) CD99 and (E) MT1-MMP in GBM cells. Shown are the means + S.D. of at least three independent experiments. Statistical analysis was performed with the paired t-test.
