AI |
aromatase inhibitors |
ALDH+ |
aldehyde dehydrogenase positive |
ARG-1 |
arginase-1 |
BC |
breast cancer |
BCs |
breast cancer cells |
BCSCs |
breast cancer stem cells |
bHLH |
Hes/Hey family of basic helix–loop–helix |
CAFs |
cancer-associated fibroblasts |
CBF-1 |
centromere binding factor 1 |
CCL17 |
C-C motif chemokine ligand 17 |
CCL2 |
C-C motif chemokine ligand 2 |
CCL22 |
C-C motif chemokine ligand 22 |
CCND1 |
cyclin D1 |
CCR2 |
C-C chemokine receptor type 2 |
CDKI |
cyclin-dependent kinase inhibitor |
ChemoR |
chemokines receptors |
CSCs |
cancer stem-like cells |
CSF-1 |
colony stimulating factor-1 |
DCIS |
ductal carcinoma in situ |
E2 |
estradiol |
ECM |
extracellular matrix |
EGF |
epidermal growth factor |
EMT |
epithelial mesenchymal transition |
ER |
estrogen receptor |
ER+ |
estrogen receptor alpha positive |
ER− |
estrogen receptor alpha negative |
ErbB1 |
human epidermal growth factor receptor |
ErbB2 |
human epidermal growth factor receptor 2 |
ErbB3 |
human epidermal growth factor receptor 3 |
ERα |
estrogen receptor alpha |
GFRs |
growth factor receptors |
GFs |
growth factors |
GPER |
G protein-coupled estrogen receptor 1 |
GSIs |
γ-secretase inhibitors |
GSK3-β |
glycogen synthase kinase 3 beta |
HER2 |
human epidermal growth factor receptor 2 |
HER2+ |
human epidermal growth factor receptor 2 positive |
HIF-1α |
hypoxia-inducible factor 1 alpha |
HIF-2α |
hypoxia-inducible factor 2 alpha |
IL-10 |
interleukin-10 |
IL-1β |
interleukin-1 beta |
IL-4 |
interleukin-4 |
IL-6 |
interleukin-6 |
IRF8 |
interferon regulatory factor 8 |
JAG |
membrane-bound ligands Jagged |
LN |
lymph nodes |
LPS |
lipopolysaccharide |
MAML |
mastermind-like |
MAPK |
mitogen-activated protein kinase |
MMP-2 |
matrix metalloproteinase-2 |
MMP-9 |
matrix metalloproteinase-9 |
MMPs |
matrix metalloproteinases |
MMTV |
mouse mammary tumor virus |
MSCs |
mesenchymal cells |
NF-κB |
nuclear factor kappa B |
NECD |
Notch extracellular domain |
NICD |
Notch intracellular domain |
NRG1 |
neuregulin 1 |
Oct-4 |
octamer binding transcription factor 4 |
PA |
plasminogen activator |
PD1+ |
programmed death 1 positive |
PR |
progesterone receptor |
PR+ |
progesterone receptor positive |
PTEN |
phosphatase and tensin homolog |
RBPJ |
recombination signal binding protein for immunoglobulin kappa J region |
SDF-1 |
stromal cell-derived factor-1 |
STAT1 |
signal transducer and activator of transcription 1 |
TAMs |
tumor-associated macrophages |
TGF-β |
transforming growth factor beta |
TILs |
tumor-infiltrating lymphocytes |
TME |
tumor microenvironment |
TNBCs |
triple negative breast cancers |
TNF-α |
tumor necrosis factor alpha |
uPA |
urokinase-type plasminogen activator |
VEGF |
vascular endothelial growth factor |
VEGFR3 |
VEGF receptor 3 |
VEGFRs |
vascular endothelial growth factor receptors |