Valve dysfunction resulting in symptoms of heart failure |
Left-sided IE caused by S. aureus
|
Fungal or highly resistant microorganisms |
Complications: heart block, annular or aortic abscess, pseudoaneurism or fistulae |
Persistent infection (persistent bacteremia, fever > 5–7 days despite appropriate antimicrobial therapy) |
Relapsing infection (recurrence of bacteremia after a complete antibiotic course) |
Persistent vegetation and recurrent emboli despite appropriate antimicrobial therapy |
Persistent fever |