Table 3.
Univariate and multivariate Cox proportional hazards survival analyses and hazards for cerebrovascular symptoms related to carotid plaques.
| Univariate Cox Regression Analysis | Adjusted Cox Regression Analysis | ||||
|---|---|---|---|---|---|
| Survival Analysis | |||||
| Parameter | HR (95% CI) | p- Value | HR (95% CI) | Wald | p- Value |
| sST2, ng/mL | 1.012 (1.008–1.016) | <0.0001 | 1.012 (1.008–1.016) | 34.6856 | <0.0001 |
| Triglycerides, mg/dL | 1.008 (1.002–1.015) | 0.0058 | 1.008 (1.002–1.015) | 6.0960 | 0.0135 |
| Symptomatic Cerebrovascular Diseases | |||||
| Parameter | HR (95% CI) | p- Value | HR (95% CI) | Wald | p- Value |
| Smoking habit | 2.327 (1.083–4.998) | 0.0304 | |||
| Hemoglobin, g/dL | 0.841 (0.716–0.988) | 0.0347 | 0.744 (0.613–0.903) | 8.9739 | 0.0027 |
| HDL-C, mg/dL | 0.972 (0.946–0–999) | 0.0440 | |||
| LDL-C, mg/dL | 1.010 (1.001–1.020) | 0.0282 | |||
| Triglycerides, mg/dL | 1.007 (1.001–1.013) | 0.0162 | |||
| Ezetimibe | 0.151 (0.021–1.104) | 0.0102 | |||
| sST2, ng/mL | 1.013 (1.008–1.017) | <0.0001 | 1.013 (1.008–1.018) | 21.998 | <0.0001 |
Abbreviations: CI: confidential index; HDL-C: high-density lipoprotein cholesterol; HR: hazard ratio; LDL-C: low-density lipoprotein cholesterol; sST2: soluble suppressor of tumorigenicity.