Figure 2.
Effect of neoastilbin on the secretion of inflammatory cytokines in THP-1-derived macrophages. Macrophages were incubated for 24 h with LPS (1 µg/mL), followed by incubation for 0.5 h with neoastilbin, then incubating with MSU (500 µM) for an additional 23.5 h. Supernatants were analyzed by ELISA for IL-1β (A), IL-6 (B) and TNF-α (C) levels. Data in the figures represent the means ± SD; significant differences among different groups are indicated as ## p < 0.01 vs. control group, * p < 0.05, ** p < 0.01 vs. LPS+MSU group (n = 3).