Figure 6.

The structure of the SLC25A10 protein is reported in cartoon representation. The three arginine residues forming the three contact points of DIC, in the similarly located MC binding region shared by all eukaryotic organisms hosting mitochondria [43,176,177,178,179,180], are reported in stick representation and labeled. The red color in the cartoon representation in the right panel indicates the protein region (including transmembrane helices H3-H6) that is not translated due to the premature stop codon mutation.